Bot plays for 1-7 minutes then diablo crashes

[Titanium]

This is the problem of the game. This problem is publicized by Blizzard. Some users don't use bot and also have this problem.
How many game accounts are you botting? If you're having this problem when botting more than 1 accounts, you could try copy the Diablo III folder to multiple places and have each bot account associated with different Diablo III.exe.